Guilty as CHARGED: p53's expanding role in disease
نویسندگان
چکیده
منابع مشابه
ICANN: Guilty as Charged?
Strathprints is designed to allow users to access the research output of the University of Strathclyde. Unless otherwise explicitly stated on the manuscript, Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. Please check the manuscript for details of any other licences that may have been applied. You may not engage in ...
متن کاملPostmortem drug levels: innocent bystander or guilty as charged.
Determining the etiology or cause of an event in forensic cases often creates many theories. On piece of additional information which may be helpful in cases involving a drug or medication are concentrations or serum levels. Although many confounders can affect the interpretation of the drug level, it is imperative to also relate the data to the clinical scenario presented. Drug levels can be h...
متن کاملGlomerular filtration barrier and molecular segregation: guilty as charged?
The normal phenotype of the glomerular filtration barrier (GFB) and the mechanisms that underlie it have intrigued physiologists, microvascular biologists, and renal physicians for decades, especially because, in health, the multilayered barrier differentially restricts the passage of molecules of various sizes, shapes, and charges. Although poorly permeable to large lipid–insoluble or anionic ...
متن کاملCXCR3⁺CCR5⁺ T cells and autoimmune diseases: guilty as charged?
Prior to the 1990s, genetic analyses indicated that many autoimmune diseases are driven by T cell responses; however, the identity of the pathogenic T cell populations responsible for dysfunctional autoimmune responses remained unclear. Some 20 years ago, the discovery of numerous chemokines and their receptors along with the development of specific mAbs to these provided a distinct advance. Th...
متن کاملGuilty as charged: non-innocent behavior by a pincer ligand featuring a central cationic phosphenium donor.
The synthesis of a new pincer ligand containing a central cationic N-heterocyclic phosphenium donor is described. The electrophilic nature of this cationic ligand renders it non-innocent, and coordination of this ligand to a PtCl(2) fragment leads to chloride migration from Pt to the cationic phosphorus center.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Cycle
سال: 2014
ISSN: 1538-4101,1551-4005
DOI: 10.4161/15384101.2014.987627